A unifying concept in pathology create, communicate, collaborate log-in    register    myfolder       news           education            jobs          meetings           forums          links         community      home > education > e-atlas > histopathology > kidney > wilms tumor (nephroblastoma) wilms tumor (nephroblastoma)    1 2 3 4 5 6 7 8 9 10 11 12 13 14 back slide /14 image id: back to index next [wilm’s tumor / nephroblastoma]. viagra cost Wilm’s tumor (nephroblastoma) is the most common malignant pediatric renal tumor usually seen at age 2-5 years. mejor viagra viagra o viagra The tumor arises from nephrogenic blastema present in developing kidneys. viagra coupon The tumor is characteristically known to contain three histologic components including blastema, epithelial elements, and stromal elements. However, the tumor may be biphasic or rarely monophasic. best site to buy viagra This photomicrograph shows two distinct components at this magnification, blastema (arrow) and stromal elements (arrowhead). [wilm’s tumor / nephroblastoma]. This image shows all three components of a wilm’s tumor (nephroblastoma), including epithelial tubules (long arrow), blastema (arrowhead), and stroma (curved arrow). cheap viagra online Most tumors are sporadic but about 10% of tumor arise in association with specific congenital disorders including wagr syndrome, denys-drash syndrome, and beckwith-wiedemann syndrome. [wilm’s tumor / nephroblastoma]. The epithelial component of the tumor may take several appearances but most commonly tubules are seen composed of primitive tall columnar cells that may merge with undifferentiated cells. The tubular structures may resemble true rosettes of neuroblastoma causing diagnostic difficulty in rare cases. Wilm’s tumor characteristically shows loss of wt-1 or wt-2 tumor suppressor gene whereas neuroblastoma does not show this abnormality. [wilm’s tumor / nephroblastoma]. The tubules seen in wilm’s tumor contain a true lumen lined by primitive tall columnar cells whereas rosettes in neuroblastoma do not contain true lumens. In difficult cases immunohistochemistry may be performed which shows expression of neuroendocrine markers in rosettes of neuroblastoma but not in tubular structures of wilm’s tumor. [wilm’s tumor / nephroblastoma]. buy soft viagra The epithelial tubular structures may show mucinous differentiation as shown in this image. Ciliated epithelium and squamous metaplasia may also be seen. buy viagra [wilm’s tumor / nephroblastoma]. discount super viagra Blastema may be scant or abundant as shown. generic once daily viagra BETTY SARMENTO HEALER  Welcome Page